Description Indication Crystalline penicillin is used to treat a variety of severe bacterial infections, including: Pneumonia Strep throat Staph infections Diphtheria Meningitis Gonorrhea Syphilis Dosage The dosage of crystalline penicillin varies depending on the type and severity of the infection. It is typically administered intravenously (IV) or intramuscularly (IM). Here are some general guidelines: Adults: 2 to 24 million units per day, divided into doses every 4 to 6 hours. Children: Dosage is based on body weight, usually 50,000 to 300,000 units per kilogram per day, divided into doses every 4 to 6 hours. Side Effects Common side effects of crystalline penicillin include: Nausea and vomiting Diarrhea Rash Injection site reactions (pain, redness, or swelling) Oral thrush or vaginal yeast infections Serious side effects can include: Allergic reactions (hives, difficulty breathing, swelling of the face, lips, tongue, or throat) Severe skin reactions Seizures Kidney problems (dark or cloudy urine, swelling of the ankles or feet) Severe diarrhea (bloody or watery stools) Precautions Allergies: Do not use if you are allergic to penicillin or any other beta-lactam antibiotics. Medical Conditions: Inform your doctor if you have a history of kidney disease, asthma, or allergies. Pregnancy and Breastfeeding: Use only if clearly needed and prescribed by a doctor. Exercise caution if breastfeeding. Drug Interactions: Crystalline penicillin can interact with other medications, such as tetracyclines and certain blood thinners.
