Artemether and Lumefantrine Capsule should be taken with high fat food or drinks such as milk. Note that patients with acute malaria are frequently averse to food. Patients should be encouraged to resume normal eating as soon as food can be tolerated since this improves absorption of artemether and lumefantrine. In the event of vomiting within 1 hour of administration a repeat dose should be taken. For adults and children weighing 35 kg and above a standard three days treatment schedule with a total of 8 doses is recommended as follows: four capsules as a single dose at the time of initial diagnosis, again four capsules after eight hours and then four capsules twice daily (morning and evening) on each of the following two days. For Adults and children weighing 25 to less than 35 kg, a six-dose regimen is recommended with three capsules as a single dose at the time of initial diagnosis, again three capsules after eight hours and then three capsules twice daily (morning and evening) on each of the following two days. For Adults and children weighing 15 to less than 25 kg, a four-dose regimen is recommended with two capsules as a single dose at the time of initial diagnosis, again two capsules after eight hours and then two capsules twice daily (morning and evening) on each of the following two days. Dosage in elderly patients Although no studies have been carried out in the elderly, no special precautions or dosage adjustments are considered necessary in such patients.
